Korean Journal of Veterinary Research 1998;38(4):853-858.
Repeated bovine abortion associated with Neospora caninum in Korea
Jae-hoon Kim1, Eui-kyung Hwang1, Hyun-joo Sohn1, Young-hwa Jean1, Soon-seek Yoon1, Dae-yong Kim2
1National Veterinary Research and Quarantine Services
2College of Veterinary Medicine, Seoul National University
Neospora caninum에 의한 젖소의 반복유산
김재훈1, 황의경1, 손현주1, 진영화1, 윤순식1, 김대용2
1국립수의과학검역원
2서울대학교 수의과대학
Abstract
A case of repeated bovine abortion caused by Neospora caninum is described. The 3-year-old Holstein cow, which was seropositive to N caninum antibody by indirect immunofluoresent assay, aborted consecutively within a 10-month period. Two fetuses of 6- or 5-month of gestation were aborted in June 1996 and March 1997, respectively. Histologically, multifocal necrotizing encephalitis, nonsuppurative periportal hepatitis, myocarditis, and myositis were observed in both fetuses. Tachyzoites or tissue cysts detected in the brain, heart and liver were positive to N caninum but negative to Toxoplasma gondii by immunohistochemical method. The results of our study demonstrate that repeated abortion due to N caninum actually occurs in Korea. This is believed to the first report of repeated abortion associated with N caninum in Korea.
Key Words: holstein cow, repeated abortion, fetus, Neospora caninum


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