| Porcine Circovirus Infection in Weaned Pigs with Postweaning Multisystemic Wasting Syndrome in Korea |
|
Jae-hoon Kim1, In-soon Roh2, Hyun-joo Sohn2, Young-hwa Jean2, Eui-kyung Hwang3, Kyoung-jin Yoon4 |
1Department of Veterinary Medicine, Cheju National University
2Pathology Division, National Veterinary Research and Quarantine Service
3College of Life Science & Natural Resources, Sangji University
4Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University |
| 국내 이유자돈의 써코바이러스 감염에 의한 이유후전신소모성 증후군 |
|
김재훈1, 노인순2, 손현주2, 진영화2, 황의경3, 윤경진4 |
1제주대학교 수의학과
2국립수의과학검역원 병리과
3상지대학교 생명자원과학대학 동물자원학과
4아이오와 주립대학 |
|
|
| Abstract |
|
Eight nursery to grower pigs exhibiting weight loss and sudden death were diagnosed as postweaning multisystemic wasting syndrome (PMWS) based on the results of gross findings, histopathology, immunohistochemistry, fluorescent antibody test, virus isolation, PCR, serology, and electron microscopy. Groosly, the pigs had a rough hair coats and were severely emaciated. And moot lymph nodes were pale and enlarged. Lungs were not fully collapsed and exhibited 10 to 40% pale red cranioventral consolidation. Histopathologically, typical lymphohistiocytic interstitial to bronchointerstitial pneumonia, chronic lymphadenitis, severe lymphoid depletion, and basophilic intracytoplasmic inclusions were noted in the most lymphoid tissues. Porcine circovirus panicles were observed in the inguinal lymph node of the pigs by electron microscopy. Porcine circovirus type 2 (PCV2) antigens or viral DNAs were detected in the lesions of all pigs using immunohistochemistry or PCR. Two PCV2 were isolated from a homogenate of pooled lung and lymph node in 2 of the 5 pigs. Additionally, antigens of porcine reproductive and respiratory syndrome virus (PRRSV) and Hemophilus (H.) parasuis were also detected by immunofluorescent antibody test. Serologically, 55% of randomly selected sows and fattening pigs was serum antibody positive to PCV2 by an indirect fluorescent antibody (IFA) test and approximately 18 % of animals in the herd were serologically pooitive by the ELISA kit for PRRSV. To our knowledge, this is the first report of PMWS co-infected with PCV-2, PRRS, and H. parasuis in Korea. |
| Key Words:
pigs, postweaning multisystemic wasting syndrome, porcine circovirus, porcine reproductive and respiratory syndrome virus, Hemophilus parasuis |
|
PDF Links
Full text via DOI
Download Citation
