| Paratuberculosis in mouflon (ovis musimon) : A case report |
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You-Chan Bae1, Ha-Young Kim1, Heui-Jin Kim1, Soon-Seek Yoon1, Jung-Won Park1, Yong-Hwa Jean1, Kyoung-Oh Cho2, Mun-Il Kang2 |
1National Veterinary Research and Quarantine Service (NVRQS)
2College of Veterinary Medicine, Jeonnam National University |
| 무플론 요네병 발생 사례 |
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배유찬1, 김하영1, 김희진1, 윤순식1, 박중원1, 진영화1, 조경오2, 강문일2 |
1국립수의과학검역원
2전남대학교 수의과대학 |
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| Abstract |
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A 2-years-old female domesticated mouflon with a clinical history of chronic diarrhea and emaciation was submitted to NVRQS. Grossly, there were severe thickening of small intestine wall and enlargement of mesenteric lymph nodes. Microscopically, severe granulomatous inflammation was found in small and large intestine, mesenteric lymph nodes, spleen and liver. By Ziehl-Neelsen stain, innumerable acid-fast rod bacteria were found in the cytoplasm of epitheloid and Langhans type giant cells present in these organs. By PCR assay with primer pair specific for Mycobacterium avium subspecies paratuberculosis(IS 900) with small intestine sample, strong positive reaction was detected, although the organism was not isolated from this organ. Based on the results of histopathology and PCR, we concluded that the case was a typical paratuberculosis in mouflon. As far as we know, this is the first case report of paratuberculosis in mouflon Korea. |
| Key Words:
Diarrhea, Johne's disease, Mouflon, Mycobacterium avium subspecies paratuberculosis |
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