Eosinophilic granulomas in two dogs

Kim, Jae-Hoon; Jung, Ji-Youl; Kang, Sang-Chul; Lee, Young-Rak; Lee, Jin-Yong; Hwang, Eui-Kyung; Woo, Gye-Hyeong; Kim, Jae-Hoon

doi:2011.51.1.69

Korean J Vet Res > Volume 51(1); 2011 > Article

Case report

Korean Journal of Veterinary Research 2011;51(1):69-72.
DOI: https://doi.org/10.14405/kjvr.2011.51.1.069 Published online March 1, 2011.

Eosinophilic granulomas in two dogs

Jae-Hoon Kim¹, Ji-Youl Jung¹, Sang-Chul Kang¹, Young-Rak Lee², Jin-Yong Lee³, Eui-Kyung Hwang⁴, Gye-Hyeong Woo⁵, Jae-Hoon Kim¹

¹College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University
²Gangnam Animal Medical Center
³Cats and Dogs Animal Clinic
⁴College of Life Science and Natural Resources, Sangji University
⁵Department of Clinical Laboratory Science, Semyung University

Abstract

Eosinophilic granuloma is a common hypersensitive inflammatory skin disease in cats, and rare in dogs and horses. The skin biopsies of 5 years old female Cocker spaniel and 2 years old female mixed dog had the clinical signs of skin nodules with alopecia were submitted for diagnosis. Solitary skin nodules and papillary nodules were presented on the left external ear and back of Cocker spaniel and on the external ear of mixed dog, respectively. Histopathologically, epidermis of skin showed mild to severe hyperplasia with multifocal ulceration. Small to large irregular, brightly eosinophilic foci with degenerating eosinophils and homogeneous degenerated collagens were existed in the dermis of both ear and back skin. Typical 'flame figures', a mixture of degenerated collagen and degranulated eosinophils, were observed in both cases. Based on the histopathologic findings and special staining characters, 2 cases were diagnosed as canine eosinophilic granuloma. This is the first report for the eosinophilic granuloma of dogs in Korea.

Key Words: dog, eosinophilic granuloma, flame figure, nodule, skin