Subcorneal pustular dermatosis in a dog

Park, Seong-Jun

doi:2013.53.2.125

Korean J Vet Res > Volume 53(2); 2013 > Article

Case report

Korean Journal of Veterinary Research 2013;53(2):125-127.
DOI: https://doi.org/10.14405/kjvr.2013.53.2.125 Published online June 25, 2013.

Subcorneal pustular dermatosis in a dog

Seong-Jun Park

College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University

개에서 발생한 각질하 농포성 피부병 1례

박성준

충남대학교 수의과대학동물의과학연구소

Abstract

Canine Subcorneal pustular dermatosis (CSPD) represents a sterile, superficial, pustular skin disease of unknown cause but may be a variant of pemphigus foliaceus. A 7-year-old, intact female, mixed dog presented with 3-month history of pruritic multiple pustules and crusts. Direct smears from intact pustules revealed numerous nondegenerate neutrophils, some acantholytic cells, and bacterial culture was negative. Histologic examination of lesional skin showed subcorneal pustules filled with neutrophils and acantholytic cells. The direct immunofluorescence tests stained with IgG, IgA, IgM, C3 were negative. Oral administration of dapsone (1 mg/kg/q8h) was initiated and it was reduced to 1 mg/kg/q12h with good control of the lesions.

Key Words: dapsone, dog, subcorneal pustular dermatosis