Hematological and blood chemical changes of rabbits infected with viral hemorrhagic disease virus

Yoon, In-joong; Jeon, Yun-seong

Korean Journal of Veterinary Research 1990;30(1):73-78.

In-joong Yoon, Yun-seong Jeon

College of Veterinary Medicine, Seoul National University

토끼 출혈성 바이러스에 감염된 토끼의 혈액상과 혈액화학치의 변화

윤인중, 전윤성

서울대학교 수의과대학

Abstract

Hematological and blood chemical changes of rabbits infected with rabbit hemorrhagic disease virus were studied and the results were summarized as follows: 1. Total leukocyte count ($2,410{pm}1,076/{mu}l$), lymphocyte count ($1,582{pm}632.5{mu}l$) and heterophil count ($705{pm}411.1{mu}l$) were significantly decreased after 24 hours of the infection (p<0.01). However, no significant changes were observed in monocyte, eosinophil and basophil numbers. 2. A significant increase of aspartate aminotransferase (96IU/L), alanine aminotransferase (96IU/L) and alkaline phosphatase ($401.1{pm}131.8IU/L$) was observed (p<0.01). 3. A moderate increase of BUN ($26.9{pm}3.6mg/100ml$) and creatinine ($3.2{pm}1.9mg/100ml$) was observed (p<0.05). 4. No significant changes of r-GTP, thymol turbidity, glucose, cholesterol, albumin, total serum protein, fibrinogen were observed.

Key Words: rabbit hemorrhagic virus, hematology, blood chemistry