Korean Journal of Veterinary Research 2008;48(4):451-455.
Clinical blood chemistry analysis in chickens infected with reticuloendotheliosis virus
Haan-Woo Sung1, Hyuk-Moo Kwon1, Sun-Jung Kim2
1School of Veterinary Medicine, Kangwon National University
2Biopoa
세망내피증 바이러스 감염 닭에서의 혈액화학치 변화
성환우1, 권혁무1, 김선중2
1강원대학교 수의학과
2바이오포아
Abstract
Body weights and blood biochemical values in chickens infected with reticuloendotheliosis virus (REV)-HI, a Korean isolate, were studied. REV-HI causes severe body weight depression in chickens inoculated but not in chicken contact-infected. Body weights of infected chickens in 3, 4, and 5 weeks after infection were 78%, 76% and 65% of those of control respectively. Blood glucose levels in REVinfected chickens were extremely high compared with those in control (226 $geq$ 21 vs. 814 $geq$91.3 mg/dl in week 2) during the experiment period. Triglyceride levels in REV-infected chickens were significantly higher in week 2 and 3, whereas in week 4, REV-infected chickens showed significantly lower levels than the control. Blood lipase, amylase and alkaline phosphatase levels of REV-infected chickens in week 2 were significantly higher, whereas cholesterol, magnesium and calcium values in week 4 were significantly lower than the control. Other blood biochemical values such as alkaline aminotransferase, aspartate aminotransferase, and $gamma$-glutamyltransferase were nonsignificantly different from the control. These above results suggest that weight depression by REV may be related with increase of blood glucose, which indicated that REV-infected chickens could not use blood glucose as energy source.
Key Words: blood chemistry, glucose, reticuloendotheliosis virus, weight depression


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